Today, more than 3,000 patients are closely monitored for the very earliest signs of breast, ovarian, and gastrointestinal cancers. Genetic testing involves a simple blood test. The blood sample is then sent to a lab that determines if there is a mutation, or change, in the genes that raises the risk of cancer for a patient and family members. A male member of the family is diagnosed with breast cancer The patient is related to someone who has an inherited mutation known to cause cancer The patient has cancer that developed in a set of paired organs (e.g., both breasts, both kidneys) patients and families who may be at an increased risk for developing hematologic (blood) malignan- cies compared to the general population due to genetic factors. Through the Clinic, they provide genetic testing, cancer prevention counseling and strategies, and long-term follow-up of individuals with known or suspected familial myelodysplastic syndrome (MDS) and acute leukemia syndromes. Churpek, Godley, and collaborators are focusing their research efforts on identifying and studying gene mutations associated with inherited forms of MDS and acute leukemia. Through research and patient assessment, the Clinic continues to help patients stop cancer before it starts. To learn more, visit www.uchospitals.edu/ specialties/cancer/risk/index.html and call 1-855-702-8222 to make an appointment. 1 Guindalini et al., Gastroenterology 149:1446-53, 2015. Jane Churpek, M D CANCER.UCHICAGO.EDU 5