Director Geoffrey Greene, PhD
Co-Director Suzanne Conzen, MD
The objective of the Breast Cancer SPORE Developmental Research Program (DRP) is to create a streamlined and transparent mechanism for selecting exciting and novel research projects that have significant potential for translational success. Such projects may be collaborative among scientists within our SPORE or outside the SPORE environment. The projects should also be innovative, have the potential for high-impact results, and preferably be multidisciplinary. The DRP has three aims:
Aim 1: Establish a mechanism for soliciting DRP applications from investigators including those from the UCCCC and local and national SPORE communities, as well as faculty members in the biological, physical, computer, and social sciences at The University of Chicago and Argonne National Laboratory.
Aim 2: Encourage, support, and nurture interdisciplinary collaboration using the expertise of our Internal Scientific Advisory Committee.
Aim 3: Select and assess projects that help generate new hypotheses for development as primary SPORE initiatives.
Past Awardees
2009-2010
Yang-Xin Fu, MD, PhD
A Novel Treatment for Her2/neu+ Breast Cancer
Anthony Kosiakoff, PhD
Receptor Mediated Delivery of Synthetic Antibodies to Antagonize Focal Adhesion Signaling in Breast Cancer
Dorothy Sipkins, MD, PhD
In Vivo Imaging of Metastatic Breast Cancer Cell Interactions with the Bone Marrow Microenvironment
Kevin White, PhD
Systems Approch to Define Estrogen Signaling Regulators in Breast Cancer
2008-2009
Suzanne D. Conzen, MD
Gene-environment Interactions: A possible Breast Cancer Link to Physiological Stress Signaling
Lucy A. Godley, MD, PhD
Identification of Proteins that Mediate Promoter Hypermethylation in Breast Cancer Using Novel Chemical Probes
Kathleen H. Goss, PhD
Wnt Pathway Activation in Basal-like Breast Cancers
Richard B. Jones, PhD
Quantitative Analysis of Ninety-six Protein Targets in Triple Negative Breast Tumors and Generation of Next Generation Clinical Screening Technology
Marvin W. Makinen, MD, PhD
Vanadyl (VO2+) Chelates Can Enhance Detection of Breast Cancer by FDG PET Imaging
Rita Nanda, MD
The role of VEGFR-2 Genetic Variation in Breast Cancer
Marsha R. Rosner, PhD
Analysis of Epac and Rap1 in Angiogenesis and Tumorigenesis of Breast Cancer
2007-2008
Philip P. Connell, MD
Targeted Inhibition of Homologous Recombinational DNA Repair in Breast Cancer Cells
Kay F. Macleod, PhD
BNIP3 as a Breast Cancer Metastasis Suppressor
