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A Comprehensive Cancer Center Designated by the National Cancer Institute

Biostatistics Core Facility

Scientific Director: Ronald Thisted, PhD
Technical Director: Theodore Karrison, PhD

The Biostatistics Core Facility provides collaborative statistical support to investigators for the design, conduct, and analysis of clinical trials, observational and population-based studies, and basic science research projects.


  • Collaborate with investigators in the formulation of study design and data analysis plans, including sample-size and power calculations
  • Assist in the development, execution, and statistical analysis of investigator-initiated Phase I, Phase II, and Phase III clinical trials and correlative/translational studies
  • Collaborate in the design and analysis of prospective and retrospective observational studies, basic science research projects, and animal experiments
  • Interact closely with the Cancer Clinical Trials Office (CCTO) and UCCCC IT group on the construction of case report forms and databases to ensure the accuracy, timeliness, and quality of research data
  • Interact with the newly developed Bioinformatics Core to assist investigators with the analysis of DNA microarray data, genome-wide association studies (GWAS), sequence analysis, and other large sets of data
  • Collaborate with investigators on the preparation of manuscripts for publication
  • Assist in new grant submissions
  • Participate in the review of clinical protocols through membership on the Clinical Trials Review Committee and the Scientific and Accrual Monitoring Committee
  • Participate in the teaching and training of investigators in fundamental statistical concepts, study design, and clinical trials methodology
  • Perform statistical methodological research related to UCCCC projects and activities